Teicoplanin A2
Names
[ CAS No. ]:
61036-64-4
[ Name ]:
Teicoplanin A2
[Synonym ]:
Teicoplanin A 2
SF 8327 factor A2
Teicoplanin A2 complex
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Melting Point ]:
260ºC
[ Molecular Formula ]:
C90H99Cl2N9O34
[ Molecular Weight ]:
1921.695
[ Exact Mass ]:
1919.567139
[ PSA ]:
671.64000
[ LogP ]:
0.12
[ Index of Refraction ]:
1.750
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WY1550000
- CHEMICAL NAME :
- Teichomycin A2
- CAS REGISTRY NUMBER :
- 61036-64-4
- LAST UPDATED :
- 199209
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 31,276,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 31,276,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 48HGAR "Current Chemotherapy and Immunotherapy, Proceedings of the International Congress of Chemotherapy, 12th, 1981," Periti, P., and G. Gialdroni-Grassi, eds., 2 vols., Washington, DC, American Soc. for Microbiology, 1982 Volume(issue)/page/year: 12,342,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 275 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 31,276,1978