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LH-21

Names

[ CAS No. ]:
611207-11-5

[ Name ]:
LH-21

[Synonym ]:
1H-1,2,4-Triazole, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-
lh 21
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole
LH-21

Biological Activity

[Description]:

LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats., and displays efficacy as a feeding inhibitor[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[References]

[1]. Francisco Javier Pavon, et al. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole--LH 21. Neuropharmacology

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
545.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H20Cl3N3

[ Molecular Weight ]:
408.75

[ Flash Point ]:
283.5±32.9 °C

[ Exact Mass ]:
407.072296

[ PSA ]:
30.71000

[ LogP ]:
8.65

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.618

Related Compounds