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Licoflavone A

Names

[ CAS No. ]:
61153-77-3

[ Name ]:
Licoflavone A

[Synonym ]:
7-Hydroxy-2-(4-hydroxy-phenyl)-6-(3-methyl-but-2-enyl)-chromen-4-one
licoflavone A
Licoflavon-A
licoflavanone A

Biological Activity

[Description]:

Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC50 of 54.5 μM[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Research Areas >> Neurological Disease

[Target]

IC50: 54.5 μM (PTP1B)[1]


[References]

[1]. Li S, et al. Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5398-401.

Chemical & Physical Properties

[ Density]:
1.279±0.06 g/cm3(Predicted)

[ Boiling Point ]:
551.1±50.0 °C(Predicted)

[ Molecular Formula ]:
C20H18O4

[ Molecular Weight ]:
322.35500

[ Exact Mass ]:
322.12100

[ PSA ]:
70.67000

[ LogP ]:
4.37990

Related Compounds