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Cysteine protease inhibitor-2

Names

[ CAS No. ]:
612048-23-4

[ Name ]:
Cysteine protease inhibitor-2

[Synonym ]:
9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-(hydroxyimino)-, (9E)-
(9E)-9-(Hydroxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile

Biological Activity

[Description]:

Cysteine protease inhibitor-2 is a cysteine protease inhibitor extracted from patent US20070032499A1, compound 12. Cysteine protease inhibitor-2 inhibits the cells growth of DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[Target]

Cysteine protease[1]


[References]

[1]. Philippe Guedat, et al. Novel cysteine protease inhibitors and their therapeutic applications. US20070032499A1.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
597.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H5N5O

[ Molecular Weight ]:
247.212

[ Flash Point ]:
315.0±30.1 °C

[ Exact Mass ]:
247.049408

[ LogP ]:
1.13

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.795

Related Compounds