3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN

Names

[ Name ]:
3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN

[Synonym ]:
3-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one
3-Chloro-4-methyl-7-hydroxycoumarin
Coumarin, 3-chloro-7-hydroxy-4-methyl-
EINECS 228-217-8
2H-1-Benzopyran-2-one, 3-chloro-7-hydroxy-4-methyl-
3-chloro-7-hydroxy-4-methylchromen-2-one
MFCD00006851
3-CHLORO-7-HYDROXY-4-METHYLCOUMARIN

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
405.8±45.0 °C at 760 mmHg

[ Melting Point ]:
240-244 °C(lit.)

[ Molecular Formula ]:
C₁₀H₇ClO₃

[ Molecular Weight ]:
210.614

[ Flash Point ]:
199.2±28.7 °C

[ Exact Mass ]:
210.008377

[ PSA ]:
50.44000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.637

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Evaluation of coumaphos exposure among tick eradication workers.

J. Occup. Environ. Med. 52(2) , 131-6, (2010)

To evaluate both the cholinesterase monitoring program and newer field methods of determining coumaphos exposure among tick eradication workers.Measured blood cholinesterase by the Ellman and field te...

Biodegradation of coumaphos, chlorferon, and diethylthiophosphate using bacteria immobilized in Ca-alginate gel beads.

Bioresour. Technol. 100(3) , 1138-42, (2009)

Calcium-alginate immobilized cell systems were developed for the detoxification and biodegradation of coumaphos, an organophosphate insecticide, and its hydrolysis products, chlorferon and diethlythio...

Management of the diffusion of 4-methylumbelliferone across phases in microdroplet-based systems for in vitro protein evolution.

Electrophoresis 31(18) , 3121-8, (2010)

Fluorongenic reagents based on 4-methylumbelliferone (4-MU) have been widely used for the detection of phosphatase, sulfatase, esterase, lipase and glycosidase activities in conventionally formatted e...