SK-7041

A potent HDAC inhibitor with IC50 of 172 nM; preferentially inhibit class I HDAC1 and HDAC2 than the other HDAC isotypes; exhibits potent antiproliferative activity against various human cancer cells in vitro, and reduces the growth of implanted human tumors in nude mice.

References 1. Ryu JK, et al. Cancer Lett. 2006 Jun 8;237(1):143-54. 2. Park JH, et al. Clin Cancer Res. 2004 Aug 1;10(15):5271-81. 3. Lee KW, et al. Anticancer Res. 2006 Sep-Oct;26(5A):3429-38. View Related Products by Target HDAC