Silicon dioxide

Names

[ Name ]:
Silicon dioxide

[Synonym ]:
Dioxosilane
diatomite
EINECS 293-303-4
MFCD00132803
Cristobalite
Diatomaceous earth, Diatomaceous silica, Kieselguhr
Silane, dioxo-
Celite S Filter Aid

Biological Activity

[Description]:

Celite can be used as an excipient, such as filter media, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
0.47 g/cm3 (loose weight)(lit.)

[ Boiling Point ]:
2200ºC

[ Melting Point ]:
1400-1650ºC

[ Molecular Formula ]:
O₂Si

[ Molecular Weight ]:
60.084

[ Exact Mass ]:
59.966755

[ PSA ]:
34.14000

[ Stability ]:
Stable. Incompatible with strong acids

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VV7311000

CHEMICAL NAME :: Silica, amorphous - diatomaceous earth

CAS REGISTRY NUMBER :: 61790-53-2

LAST UPDATED :: 199712

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R36/37;R48/20

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
VV7311000

[ HS Code ]:
3802900090

Customs

[ HS Code ]: 3802900090

Articles

Seawater ultrafiltration: role of particles on organic rejections and permeate fluxes.

Environ. Technol. 34(17-20) , 2553-61, (2013)

The role of natural compounds of seawater and added particles on mechanisms of membrane fouling and organic matter rejection has been investigated. Ultrafiltration (100 kDa) has been conducted in both...

Removal of aniline and phenol from water using raw and aluminum hydroxide-modified diatomite.

Water Sci. Technol. 67(7) , 1620-6, (2013)

The feasibility of using raw diatomite and aluminum hydroxide-modified diatomite (Al-diatomite) for removal of aniline and phenol from water was investigated. Their physicochemical characteristics suc...

[Preparation and applications of a supported liquid-liquid extraction column with a composite diatomite material].

Se Pu 30(8) , 798-803, (2012)

A rapid and special supported liquid-liquid extraction (SLE) column was developed with a composite diatomite material. The SLE column was evaluated by high performance liquid chromatography (HPLC) wit...