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H-Ala-Ala-Phe-AMC (free base)

Names

[ CAS No. ]:
62037-41-6

[ Name ]:
H-Ala-Ala-Phe-AMC (free base)

[Synonym ]:
2-[2-(2-aminopropanoylamino)propanoylamino]-N-(4-methyl-2-oxochromen-7-yl)-3-phenylpropanamide

Chemical & Physical Properties

[ Density]:
1.286g/cm3

[ Boiling Point ]:
831ºC at 760 mmHg

[ Molecular Formula ]:
C25H28N4O5

[ Molecular Weight ]:
464.51400

[ Flash Point ]:
456.4ºC

[ Exact Mass ]:
464.20600

[ PSA ]:
143.53000

[ LogP ]:
3.17440

[ Index of Refraction ]:
1.616

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates.

Anal. Biochem. 78 , 47, (1977)

Sensitive fluorogenic substrates for trypsin, chymotrypsin, and elastase were prepared. These substrates are amides of an acyl amino acid or peptide with 7-amino-4-methylcoumarin (AMC). The substrates...

Purification, substrate specificity, and classification of tripeptidyl peptidase II.

J. Biol. Chem. 261 , 2409, (1986)

An extralysosomal tripeptide-releasing aminopeptidase was recently discovered in rat liver (Bålöw, R.-M., Ragnarsson, U., and Zetterqvist, O. (1983) J. Biol. Chem. 258, 11622-11628). In the present wo...

Protracted late infantile ceroid lipofuscinosis due to TPP1 mutations: Clinical, molecular and biochemical characterization in three sibs.

J. Neurol. Sci. 356 , 65-71, (2015)

This work investigated the molecular cause responsible for a late-onset parkinsonism-dystonia phenotype in three Italian siblings, and clinically characterize this condition.Extensive neurophysiologic...


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