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Wee1 Inhibitor I

Names

[ CAS No. ]:
622855-37-2

[ Name ]:
Wee1 Inhibitor I

[Synonym ]:
Wee1 Inhibitor
Kinome_3672
HMS3229P19

Biological Activity

[Description]:

WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Wee1

[Target]

IC50: 0.011 μM (Wee1 kinase) pIC50: 7.96[1]

[References]

[1]. Kanin Wichapong, et al. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₁ClN₂O₃

[ Molecular Weight ]:
362.76600

[ Exact Mass ]:
362.04600

[ PSA ]:
85.68000

[ LogP ]:
4.24110

Related Compounds