2-indol-3-yl-4-oxo-4-phenylbutanoic acid

Names

[ Name ]:
2-indol-3-yl-4-oxo-4-phenylbutanoic acid

[Synonym ]:
2-(1H-indol-3-yl)-4-oxo-4-phenylbutanoic acid

Biological Activity

[Description]:

PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[In Vitro]

PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCFTIR1/AFBs. PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize[1].

[References]

[1]. Nishimura T, et al. Differential downward stream of auxin synthesized at the tip has a key role in gravitropic curvature via TIR1/AFBs-mediated auxin signaling pathways. Plant Cell Physiol. 2009 Nov;50(11):1874-85.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.318 g/cm3

[ Boiling Point ]:
569ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₅NO₃

[ Molecular Weight ]:
293.31700

[ Flash Point ]:
297.9ºC

[ Exact Mass ]:
293.10500

[ PSA ]:
70.16000

[ LogP ]:
3.60910

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%