Antimycobacterial agent-2

Names

[ CAS No. ]:
62670-49-9

[ Name ]:
Antimycobacterial agent-2

Biological Activity

[Description]:

Antimycobacterial agent-2 (compound 58) is a potent antimycobacterial agent. Antimycobacterial agent-2 shows anti-mycobacterial activities with an MIC99 of 0.8 µM for Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 shows cytotoxic activities with an IC50 of48.1 µM for CHO cells[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Singh K, et al. Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity. Bioorg Med Chem. 2020 Jul 1;28(13):115530.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H50O5

[ Molecular Weight ]:
502.73

Related Compounds