H-D-Arg-OH.HCl

Names

[ CAS No. ]:
627-75-8

[ Name ]:
H-D-Arg-OH.HCl

[Synonym ]:
Arginine, monohydrochloride, D-
EINECS 211-010-1
D-Arginine hydrochloride (1:1)
D-Arginine monohydrochloride
D-Arginine, hydrochloride (1:1)
MFCD00012620
H-D-Arg-OH.HCl

Biological Activity

[Description]:

H-D-Arg-OH.HCl is an arginine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
409.1ºC at 760 mmHg

[ Melting Point ]:
216-218ºC

[ Molecular Formula ]:
C₆H₁₅ClN₄O₂

[ Molecular Weight ]:
210.662

[ Flash Point ]:
201.2ºC

[ Exact Mass ]:
210.088348

[ PSA ]:
125.22000

[ LogP ]:
1.35480

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CF1995000

CHEMICAL NAME :: Arginine, monohydrochloride, D-

CAS REGISTRY NUMBER :: 627-75-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H14-N4-O2.Cl-H

MOLECULAR WEIGHT :: 210.70

WISWESSER LINE NOTATION :: MUYZM3YZVQ &QH -D

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3582 mg/kg

TOXIC EFFECTS :: Behavioral - coma Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CF1995000

[ HS Code ]:
2925290090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

D-arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an eNOS-independent mechanism Dahr, I., et al.

J. Pharmacol. Exp. Ther. 63 , 196-204, (2012)

A simple method of preparing D-(minus)-arginine monohydrochloride from DL-arginine.

Anal. Biochem. 63 , 68-72, (1975)