Benzoate-d5 sodium

Names

[ CAS No. ]:
62790-26-5

[ Name ]:
Benzoate-d5 sodium

[Synonym ]:
Benzoic acid-2,3,4,5,6-d5 sodium salt
Sodium benzoate-d5

Biological Activity

[Description]:

Benzoate-d5 (sodium) is the deuterium labeled Sodium benzoate[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
>300ºC(lit.)

[ Molecular Formula ]:
C₇D₅NaO₂

[ Molecular Weight ]:
149.13400

[ Flash Point ]:
121ºC

[ Exact Mass ]:
149.05000

[ PSA ]:
40.13000

[ LogP ]:
0.05010

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H317-H318-H334-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-37/38-41-42/43

[ Safety Phrases ]:
22-26-36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

Articles

Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans.

Mol. Genet. Metab. 114(1) , 73-9, (2014)

Sodium benzoate is a widely used preservative found in many foods and soft drinks. It is metabolized within mitochondria to produce hippurate, which is then cleared by the kidneys. We previously repor...