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Fmoc-NH-PEG5-CH2COOH

Names

[ CAS No. ]:
635287-26-2

[ Name ]:
Fmoc-NH-PEG5-CH2COOH

[Synonym ]:
Fmoc-NH-5(ethylene glycol)-acetic acid
FMOC-NH-DPEG5-COOH
Fmoc-NH-PEG5-CH2COOH
Fmoc-NH-5(ethylene glycol)-actic acid
5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

Biological Activity

[Description]:

Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Liuhong CHEN, et al. Multimeric bicyclic peptide ligands. WO2019162682A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H35NO9

[ Molecular Weight ]:
517.56800

[ Exact Mass ]:
517.23100

[ PSA ]:
121.78000

[ LogP ]:
3.08360

[ Storage condition ]:
2-8°C


Related Compounds