n-(4-aminophenyl)-4-methylbenzenesulfonamide

Names

[ CAS No. ]:
6380-08-1

[ Name ]:
n-(4-aminophenyl)-4-methylbenzenesulfonamide

[Synonym ]:
4-p-toluenesulphonamido-aniline
MFCD00134366
N-p-Toluolsulfonyl-p-phenylendiamin

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
453.7ºC at 760 mmHg

[ Melting Point ]:
183-185 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₄N₂O₂S

[ Molecular Weight ]:
262.32700

[ Flash Point ]:
228.2ºC

[ Exact Mass ]:
262.07800

[ PSA ]:
80.57000

[ LogP ]:
4.11300

[ Index of Refraction ]:
1.653

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

N-(4-Amino-phen-yl)-4-methylbenzene-sulfonamide.

Acta Crystallogr. Sect. E Struct. Rep. Online 67(10) , o2709-o2709, (2011)

The title compound, C(13)H(14)N(2)O(2)S, crystallized with two independent mol-ecules in the asymmetric unit. They both have V-shaped conformations: the dihedral angles between their benzene rings are...

2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion.

Bioorg. Med. Chem. 22(22) , 6459-70, (2014)

A novel series of 8-amino imidazo[1,2-a]pyrazine derivatives has been developed as inhibitors of the VirB11 ATPase HP0525, a key component of the bacterial type IV secretion system. A flexible synthet...