Oxotremorine M
Names
[ CAS No. ]:
63939-65-1
[ Name ]:
Oxotremorine M
[Synonym ]:
Oxotremorine M,N,N,N-Trimethyl-4-(2-oxo-1-pyrolidinyl)-2-butyn-1-ammoniumiodide
MFCD00055133
Chemical & Physical Properties
[ Melting Point ]:
154 - 156 °C
[ Molecular Formula ]:
C11H19IN2O
[ Molecular Weight ]:
322.18600
[ Exact Mass ]:
322.05400
[ PSA ]:
20.31000
[ Storage condition ]:
2-8°C
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T
[ Risk Phrases ]:
26/27/28
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
UN 2810 6.1/PG 2
[ RTECS ]:
ER9552000
[ HS Code ]:
2933790090
Customs
[ HS Code ]: 2933790090
[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%
Articles
Neurosci. Lett. 593 , 129-33, (2015)
Our previous investigations have revealed that cerebellar cholinergic innervation is involved in cardiovascular regulation. This study was performed to examine the effects of the muscarinic cholinergi...
Anti-muscarinic adjunct therapy accelerates functional human oligodendrocyte repair.J. Neurosci. 35(8) , 3676-88, (2015)
Therapeutic repair of myelin disorders may be limited by the relatively slow rate of human oligodendrocyte differentiation. To identify appropriate pharmacological targets with which to accelerate dif...
The guinea pig ileum lacks the direct, high-potency, M(2)-muscarinic, contractile mechanism characteristic of the mouse ileum.Naunyn Schmiedebergs Arch. Pharmacol. 380(4) , 327-35, (2009)
We explored whether the M(2) muscarinic receptor in the guinea pig ileum elicits a highly potent, direct-contractile response, like that from the M(3) muscarinic receptor knockout mouse. First, we cha...