1,4,8,11-TETRAAZACYCLOTETRADECANE-5,7-DIONE

Names

[ Name ]:
1,4,8,11-TETRAAZACYCLOTETRADECANE-5,7-DIONE

[Synonym ]:
4,7,11,14-Tetraazacyclotetradecane-1,3-dione
1,4,8,12-tetraazacyclotetradecane-5,7-dione
5,7-dioxo-1,4,8,11-tetra-azacyclo-tetradecane
1,4,8,11-tetraazacyclotetradecane-12,14-dione
IPS104
MFCD00075005
1,4,8,11,-tetraazacyclotetradecane-5,7-dione
cis-dioxocyclam
Dioxocyclam

Chemical & Physical Properties

[ Density]:
1.012 g/cm3

[ Boiling Point ]:
552.1ºC at 760 mmHg

[ Melting Point ]:
172-176ºC(lit.)

[ Molecular Formula ]:
C₁₀H₂₀N₄O₂

[ Molecular Weight ]:
228.29100

[ Flash Point ]:
234.8ºC

[ Exact Mass ]:
228.15900

[ PSA ]:
82.26000

[ Index of Refraction ]:
1.442

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
26-28-36/37/39-45

[ RIDADR ]:
UN 3259 8

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The synthesis and radiolabeling of 2-nitroimidazole derivatives of cyclam and their preclinical evaluation as positive markers of tumor hypoxia.

J. Nucl. Med. 43(6) , 837-50, (2002)

The cyclam ligand (1,4,8,11-tetraazacyclotetradecane) was condensed with various azomycin-containing synthons to produce chemical compounds that could chelate radioactive metals. It was expected that ...

Chemistry of constrained dioxocyclam ligands with Co(III): unusual examples of C-H and C-N bond cleavage.

Inorg. Chem. 42(23) , 7602-7, (2003)

The reactions between H(2)dc3 and Co(acac)(3) have been studied in the presence and absence of base. In the presence of base, a complex with an intramolecular Co-C bond, Co(dc3-C-(8))(H(2)O), 1, is fo...

N-functionalization of poly(ethylene glycol)-linked mono- and bis-dioxocyclams as potential ligands for Gd3+.

J. Org. Chem. 68(22) , 8409-15, (2003)

A number of highly functionalized dioxocyclams with acetic acid side chains on the secondary amine sites and ethylene glycol side chains on 6 and 13-positions (12a, 12b) or a tetra(ethylene glycol) si...