Ethanaminium,2-chloro-N-(2-chloroethyl)-N,N-dimethyl-, chloride (9CI)
Names
[ CAS No. ]:
63977-49-1
[ Name ]:
Ethanaminium,2-chloro-N-(2-chloroethyl)-N,N-dimethyl-, chloride (9CI)
[Synonym ]:
tl 379
Chemical & Physical Properties
[ Molecular Formula ]:
C6H14Cl3N
[ Molecular Weight ]:
206.54100
[ Exact Mass ]:
205.01900
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BO8925000
- CHEMICAL NAME :
- Ammonium, bis(2-chloroethyl)dimethyl-, chloride
- CAS REGISTRY NUMBER :
- 63977-49-1
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H14-Cl2-N.Cl
- MOLECULAR WEIGHT :
- 206.56
- WISWESSER LINE NOTATION :
- G2K1&1&2G &Q &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 43,171,1952
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1700 mg/m3/10M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,SEP1942
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 67 mg/kg
- TOXIC EFFECTS :
- Blood - other changes Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948- Volume(issue)/page/year: 2,1055,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 91,224,1947