H-Ser-Glu-OH

Names

[ CAS No. ]:
6403-16-3

[ Name ]:
H-Ser-Glu-OH

[Synonym ]:
N-L-Seryl-L-glutaminsaeure
N-L-seryl-L-glutamic acid
Ser-Glu
serylglutamic acid
L-Seryl=>L-glutaminsaeure

Biological Activity

[Description]:

(S)-2-((S)-2-Amino-3-hydroxypropanamido)pentanedioic acid is a glutamic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₄N₂O₆

[ Molecular Weight ]:
234.20700

[ Exact Mass ]:
234.08500

[ PSA ]:
153.44000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides.

J. Med. Chem. 40 , 3534-3541, (1997)

We have rationally designed a sLe(x) mimetic based on molecular modeling, synthesized type II and type II' beta-turn dipeptides (3a,b), and evaluated their biological profiles both in vitro and in viv...

Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry.

Future Med. Chem. 2 , 587-599, (2010)

Several glycoprocessing enzymes and glycoreceptors have been recognized as important targets for therapeutic intervention. This concept has inspired the development of important classes of therapeutic...

Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides.

J. Med. Chem. 41 , 4279-4287, (1998)

We have previously found that heterochiral fucodipeptides, L-Ser-D-Glu (3a) and D-Ser-L-Glu (3b), exhibited up to 20-100 times more potency than a sialyl Lewis X (sLeX, 1) and a 3'-sulfated Lewis X an...