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2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-β-D-ribofuranosyl)]-9H-purine

Names

[ CAS No. ]:
641571-44-0

[ Name ]:
2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-β-D-ribofuranosyl)]-9H-purine

[Synonym ]:
6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine
9H-Purin-2-amine, 6-chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-

Biological Activity

[Description]:

2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine dibenzoate is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
816.3±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H26ClN5O7

[ Molecular Weight ]:
628.03

[ Flash Point ]:
447.5±37.1 °C

[ Exact Mass ]:
627.152100

[ LogP ]:
7.85

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.684

Related Compounds