Acetaminophen-D4
Names
[ CAS No. ]:
64315-36-2
[ Name ]:
Acetaminophen-D4
[Synonym ]:
N-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)acetamide
Chemical & Physical Properties
[ Melting Point ]:
169-171°C (dec.)
[ Molecular Formula ]:
C8H5D4NO2
[ Molecular Weight ]:
155.18700
[ Flash Point ]:
9℃
[ Exact Mass ]:
155.08800
[ PSA ]:
49.33000
[ LogP ]:
1.42360
[ Storage condition ]:
-20°C Freezer
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Hazard Codes ]:
Xn,T,F
[ Risk Phrases ]:
22-36/37/38-39/23/24/25-23/24/25-11
[ Safety Phrases ]:
26-36-45-36/37-16-7
[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Drug Metab. Dispos. 42(12) , 2058-67, (2014)
N-(2,4-dichlorophenyl)-5-methyl-1,2-oxazole-3-carboxamide (UTL-5g), a potential chemo- and radioprotective agent, acts as a prodrug requiring bioactivation to the active metabolite 5-methylisoxazole-3...
Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds.Drug Metab. Dispos. 44 , 435-44, (2016)
In vitro models based on primary human hepatocytes (PHH) have been advanced for clearance (CL) prediction of metabolically stable compounds, representing state-of-the-art assay systems for drug discov...
Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.J. Appl. Toxicol. 36 , 320-9, (2016)
Cytochrome P450 (CYP) induction is a key risk factor of clinical drug-drug interactions that has to be mitigated in the early phases of drug discovery. Three-dimensional (3D) cultures of hepatocytes i...