1-Methylhistamine dihydrochloride

Names

[ CAS No. ]:
6481-48-7

[ Name ]:
1-Methylhistamine dihydrochloride

[Synonym ]:
1-methylhistamine dihydrochloride

Biological Activity

[Description]:

1-Methylhistamine dihydrochloride is a histamine metabolite[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

1-Methylhistamine is a product of histamine 1-methyltransferase in the pathway of histidine metabolism[1].

[References]

[1]. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₃Cl₂N₃

[ Molecular Weight ]:
161.63300

[ Exact Mass ]:
161.07200

[ PSA ]:
43.84000

[ LogP ]:
1.42360

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933290090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age.

Clin. Chim. Acta 378(1-2) , 122-7, (2007)

According to a previous study, the concentration of HA in the hair of SD rats was similar in each rat and the variation in HA concentration was not so great. However, the concentration in human hair w...

The interaction of parafluorohexahydrosiladiphenidol at muscarinic receptors in vitro.

Br. J. Pharmacol. 99 , 637, (1990)

1. The antagonistic actions of parafluorohexahydrosiladiphenidol (pFHHSiD) at muscarinic receptors has been studied in cardiac muscle, smooth muscle and cell culture preparations. In this paper, the c...

High-performance liquid chromatographic determination of histamine in biological samples: the cerebrospinal fluid challenge--a review.

Anal. Chim. Acta 774 , 1-10, (2013)

Histamine, a neurotransmitter crucially involved in a number of basic physiological functions, undergoes changes in neuropsychiatric disorders. Detection of histamine in biological samples such as cer...