1,2-Propanediamine,N1,N1-dimethyl-N2-(1-nitro-9-acridinyl)-, hydrochloride (1:2)
Names
[ CAS No. ]:
65094-73-7
[ Name ]:
1,2-Propanediamine,N1,N1-dimethyl-N2-(1-nitro-9-acridinyl)-, hydrochloride (1:2)
Chemical & Physical Properties
[ Density]:
1.267g/cm3
[ Boiling Point ]:
512.7ºC at 760 mmHg
[ Molecular Formula ]:
C18H21ClN4O2
[ Molecular Weight ]:
360.83800
[ Flash Point ]:
263.9ºC
[ Exact Mass ]:
360.13500
[ PSA ]:
73.98000
[ LogP ]:
5.05640
[ Index of Refraction ]:
1.695
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX7955000
- CHEMICAL NAME :
- 1,2-Propanediamine, N(sup 1),N(sup 1)-dimethyl-N(sup 2)-(1-nitro-9-acridinyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 65094-73-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C18-H20-N4-O2.2Cl-H
- MOLECULAR WEIGHT :
- 397.34
- WISWESSER LINE NOTATION :
- T C666 BNJ GNW IMY1&1N1&1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - decreased motility or constipation Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 99200 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - decreased motility or constipation Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 80 nmol/L/69H
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,93,1979