Mating Factor α (1-6) acetate salt

Names

[ Name ]:
Mating Factor α (1-6) acetate salt

[Synonym ]:
alpha1-Mating factor fragment-1-6
A1-Mating factor fragment 1-6
Trp-His-Trp-Leu-Gln-Leu
a-Mating Factor: 1-6

Biological Activity

[Description]:

Mating Factor α (1-6) is a mating factor produced by α-mating type cells of Saccharomyces cerevisiae and an acts as an inhibitor of the initiation of DNA synthesis in the cells[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[Target]

DNA synthesis[1]

[References]

[1]. Tanaka T, et al. Degradation of mating factor by α-mating type cells of Saccharomyces cerevisiae. The Journal of Biochemistry, 1977, 82(6): 1689-1693.

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
1395.3ºC at 760 mmHg

[ Molecular Formula ]:
C₄₅H₅₉N₁₁O₈

[ Molecular Weight ]:
882.01900

[ Flash Point ]:
797.6ºC

[ Exact Mass ]:
881.45500

[ PSA ]:
312.17000

[ LogP ]:
4.94890

[ Index of Refraction ]:
1.636

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Influence of DNA repair deficiencies on the UV sensitivity of yeast cells in different cell cycle stages.

Mutat. Res. 245(4) , 287-92, (1990)

Synchronously dividing haploid yeast cells were UV-irradiated in various stages of the cell cycle after release from alpha-factor arrest. In confirmation of earlier results (Chanet et al., 1973), in w...

A multiplex serum protein assay for determining the probability of colorectal cancer.

Am. J. Cancer Res. 2(5) , 598-605, (2012)

Our purpose is to develop a serum assay to determine an individual's probability of having colorectal cancer (CRC). We have discovered a protein panel yielding encouraging, clinically significant resu...

Probing the functional conformation of the tridecapeptide mating pheromone of Saccharomyces cerevisiae through study of disulfide-constrained analogs.

Int. J. Pept. Protein Res. 47 , 131-141, (1996)

Analogs of the Saccharomyces cerevisiae alpha-mating factor, Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, where Lys7 and Gln10 were replaced with Cys, Cys(CH3), or Ser, were synthesized using ...