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BW 246C

Names

[ CAS No. ]:
65705-83-1

[ Name ]:
BW 246C

[Synonym ]:
4-Imidazolidineheptanoic acid, 3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxo-, (4R)-
8-epi bw 245c
7-{(4R)-3-[(3R)-3-Cyclohexyl-3-hydroxypropyl]-2,5-dioxo-4-imidazolidinyl}heptanoic acid
bw 246c

Biological Activity

[Description]:

(8-epi)-BW 245C is the C-8 diastereomer of BW 245C (HY-101987). BW 245 C is a high affinity and selective PGD2 receptor agonist[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. Town MH, et al. Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors. Prostaglandins. 1983 Jan;25(1):13-28.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C19H32N2O5

[ Molecular Weight ]:
368.47

[ Exact Mass ]:
368.231110

[ PSA ]:
106.94000

[ LogP ]:
2.12

[ Index of Refraction ]:
1.521

Related Compounds