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AA38-3

Names

[ CAS No. ]:
65815-76-1

[ Name ]:
AA38-3

[Synonym ]:
4-Nitrophenyl 1-piperidinecarboxylate
4-Nitrophenyl piperidine-1-carboxylate
MFCD00276294
1-Piperidinecarboxylic acid, 4-nitrophenyl ester

Biological Activity

[Description]:

AA38-3 is a serine hydrolase (SH) inhibitor. AA38-3 can inhibit three SHs, ABHD6, ABHD11, and FAAH[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL
Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH
Research Areas >> Metabolic Disease
Signaling Pathways >> Neuronal Signaling >> FAAH

[References]

[1]. Adibekian A, et, al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
397.5±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H14N2O4

[ Molecular Weight ]:
250.25

[ Flash Point ]:
194.2±25.7 °C

[ Exact Mass ]:
250.095352

[ LogP ]:
3.21

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.579

Related Compounds