Licoisoflavone A

Names

[ Name ]:
Licoisoflavone A

[Synonym ]:
3-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-4H-chromen-4-one
3-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxychromen-4-one
4H-1-Benzopyran-4-one, 3-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-
phaseoluteone
Lico-iso-flavone A
3-[2,4-Dihydroxy-3-(3-methyl-but-2-enyl)-phenyl]-5,7-dihydroxy-1-benzopyran-4-one
Licoisoflavone A

Biological Activity

[Description]:

Licoisoflavone A, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.[1]. Licoisoflavone A inhibits lipid peroxidation with an IC50 of 7.2 μM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Li D, et al. The Application of Ultra-High-Performance Liquid Chromatography Coupled with a LTQ-Orbitrap Mass Technique to Reveal the Dynamic Accumulation of Secondary Metabolites in Licorice under ABA Stress. Molecules. 2017 Oct 20;22(10). pii: E1742.

[2]. S. Toda, et al. Inhibitory Effects of Isoflavones in Sophora mooracrotiana on Lipid Peroxidation by Superoxide. Pharmaceutical Biology. 2002, 40 (6):422-424.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
635.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₈O₆

[ Molecular Weight ]:
354.353

[ Flash Point ]:
230.9±25.0 °C

[ Exact Mass ]:
354.110352

[ PSA ]:
111.13000

[ LogP ]:
5.08

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.690

[ Storage condition ]:
2-8C

Safety Information

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%