6-amino-1,3-dimethyl-5-nitrosouracil
Names
[ CAS No. ]:
6632-68-4
[ Name ]:
6-amino-1,3-dimethyl-5-nitrosouracil
[Synonym ]:
6-amino-1,3-dimethyl-5-nitroso-uracil
1,3-dimethyl-4-amino-5-nitroso-2,6-pyrimidindione
1,3-dimethyl-4-amino-5-nitrosouracil
danu
4-Amino-1,3-dimethyl-5-nitrosouracil
6-amino-5-nitroso-1,3-dimethyluracil
6-amino-1,3-dimethyl-5-nitroso-uraci
6-amino-1,3-dimethyl-5-nitrosopyrimidine 2,4(1H,3H)-dione
Chemical & Physical Properties
[ Density]:
1.408g/cm3
[ Boiling Point ]:
513ºC at 760 mmHg
[ Melting Point ]:
241-243ºC
[ Molecular Formula ]:
C6H8N4O3
[ Molecular Weight ]:
184.15300
[ Flash Point ]:
264ºC
[ Exact Mass ]:
184.06000
[ PSA ]:
99.45000
[ Index of Refraction ]:
1.63
[ Storage condition ]:
−20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ8780000
- CHEMICAL NAME :
- Uracil, 6-amino-1,3-dimethyl-5-nitroso-
- CAS REGISTRY NUMBER :
- 6632-68-4
- BEILSTEIN REFERENCE NO. :
- 0180955
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C6-H8-N4-O3
- MOLECULAR WEIGHT :
- 184.18
- WISWESSER LINE NOTATION :
- T6NVNVJ A1 C1 ENO FZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 80,297,1973 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16 gm/kg/34W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 80,297,1973
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H351
[ Precautionary Statements ]:
P281
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
40
[ Safety Phrases ]:
22-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
YQ8780000
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%