N-Feruloyloctopamine

Names

[ Name ]:
N-Feruloyloctopamine

[Synonym ]:
2-Propenamide, N-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
N-trans-feruloyl 3-O-methyldopamine
(2E)-N-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)acrylamide
N-trans-feruloy-3-O-methyldopamine
N-trans-feruloyl octopamine
N-trans-Feruloyloctopamin
trans-N-feruloyloctopamine
trans-N-feruloyl-3-O-methyldopamine
N-trans-Feruloylmethoxytyramine
Octopamine, N-feruloyl-

Biological Activity

[Description]:

N-Feruloyloctopamine, isolated from Garlic skin, is an antioxidant constituent. N-Feruloyloctopamine significantly decreases the phosphorylation levels of Akt and p38 MAPK[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> Akt

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK

[Target]

Akt

p38 MAPK

[References]

[1]. Bai ZT, et al. Inhibition of invasion by N-trans-feruloyloctopamine via AKT, p38MAPK and EMT related signals in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2017 Feb 15;27(4):989-993.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
652.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₉NO₅

[ Molecular Weight ]:
329.347

[ Flash Point ]:
348.4±31.5 °C

[ Exact Mass ]:
329.126312

[ PSA ]:
99.02000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.656

Safety Information

[ Hazard Codes ]:
Xi

N-Feruloyloctopamine

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds