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α-Conotoxin PIA TFA

Names

[ CAS No. ]:
669050-68-4

[ Name ]:
α-Conotoxin PIA TFA

[Synonym ]:
a-conotoxin pia
arg-asp-pro-cys-cys-ser-asn-pro-val-cys-thr-val-his-asn-pro-gln-ile-cys-nh2

Biological Activity

[Description]:

α-Conotoxin PIA is a nicotinic acetylcholine receptor (nAChR) antagonist isolated from Conus purpurascens that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia[1]。

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[References]

[1]. Seung-Wook Chi, et al. Solution Structure of Alpha-Conotoxin PIA, a Novel Antagonist of alpha6 Subunit Containing Nicotinic Acetylcholine Receptors. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1990-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C79H125N27O25S4

[ Molecular Weight ]:
1981.26000

[ Exact Mass ]:
1979.82000

[ PSA ]:
936.25000

[ Storage condition ]:
-20°C

Related Compounds