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WAY-169916

Names

[ CAS No. ]:
669764-18-5

[ Name ]:
WAY-169916

[Synonym ]:
WAY-169916

Biological Activity

[Description]:

WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR
Research Areas >> Inflammation/Immunology

[References]

[1]. Chadwick CC, et al. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2543-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H13F3N2O2

[ Molecular Weight ]:
334.29

[ Exact Mass ]:
334.09300

[ PSA ]:
58.02000

[ LogP ]:
3.18680


Related Compounds