Adenosine,N-2-propynyl- (9CI)

Names

[ Name ]:
Adenosine,N-2-propynyl- (9CI)

[Synonym ]:
6-propargyl-adenosine
N6-prop-2-ynyl-adenosine
N6-Propynyladenosine
N6-propargyladenosine

Biological Activity

[Description]:

N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
1.66g/cm3

[ Boiling Point ]:
679.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₅N₅O₄

[ Molecular Weight ]:
305.29

[ Flash Point ]:
364.7ºC

[ Exact Mass ]:
305.11200

[ PSA ]:
125.55000

[ Index of Refraction ]:
1.749

Adenosine,N-2-propynyl- (9CI)

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds