H-Met-Arg-Phe-Ala-OH

Names

[ Name ]:
H-Met-Arg-Phe-Ala-OH

[Synonym ]:
H-Met-Arg-Phe-Ala
MRFA
FRAGMENT E
L-MET-ARG-PHE-ALA
MET-ARG-PHE-ALA ACETATE SALT
met-arg-phe-ala acetate

Biological Activity

[Description]:

Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Knight M, et al. Brain endopeptidase generates enkephalin from striatal precursors. Peptides. 1982 May-Jun;3(3):461-8.

Chemical & Physical Properties

[ Density]:
1.37±0.1 g/cm3(Predicted)

[ Molecular Formula ]:
C₂₃H₃₇N₇O₅S

[ Molecular Weight ]:
523.64900

[ Exact Mass ]:
523.25800

[ PSA ]:
237.82000

[ LogP ]:
2.19560

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry.

J. Steroid Biochem. Mol. Biol. 152 , 142-54, (2015)

Androsta-1,4,6-triene-3,17-dione (ATD) is an irreversible steroidal aromatase inhibitor and is marketed as a supplement. It has been reported to effectively reduce estrogen biosynthesis and significan...

Solid state compatibility study and characterization of a novel degradation product of tacrolimus in formulation.

J. Pharm. Biomed. Anal. 110 , 67-75, (2015)

Tacrolimus is macrolide drug that is widely used as a potent immunosuppressant. In the present work compatibility testing was conducted on physical mixtures of tacrolimus with excipients and on compat...

Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis.

Nat. Protoc. 3 , 1341-9, (2008)

Nanostructure-initiator mass spectrometry (NIMS) is a new surface-based MS technique that uses a nanostructured surface to trap liquid ('initiator') compounds. Analyte materials adsorbed onto this 'cl...