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5-Aza-7-deazaguanine

Names

[ CAS No. ]:
67410-64-4

[ Name ]:
5-Aza-7-deazaguanine

[Synonym ]:
2-amino-1H-imidazo[1,2-a][1,3,5]triazin-4-one

Biological Activity

[Description]:

5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[Target]

Purine nucleoside phosphorylase, Nucleoside Antimetabolite/Analog[1]


[References]

[1]. Fateev IV, et al. Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides. Chemistry. 2015 Sep 14;21(38):13401-19.

Chemical & Physical Properties

[ Molecular Formula ]:
C5H5N5O

[ Molecular Weight ]:
151.12600

[ Exact Mass ]:
151.04900

[ PSA ]:
89.07000

Related Compounds