(7-Methoxy-1-naphthyl)acetic acid

Names

[ Name ]:
(7-Methoxy-1-naphthyl)acetic acid

[Synonym ]:
2-(7-Methoxynaphthalen-1-yl)acetic acid
(7-Methoxy-1-naphthyl)acetic acid
1-Naphthaleneacetic acid, 7-methoxy-
2-(7-Methoxynaphthalen-1-yl)aceticacid
Agomelatine Impurity 7

Biological Activity

[Description]:

7-Methyl-1-naphthyl acetic acid is a potentinhibitor of auxin action in plants. 7-Methyl-1-naphthyl acetic acid inhibitsAUX1, PIN, and ABCB protein-mediated auxin transport expressed in yeast.7-Methyl-1-naphthyl acetic acid can be used in auxin dependent development[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tsuda E, et al. Alkoxy-auxins are selective inhibitors of auxin transport mediated by PIN, ABCB, and AUX1 transporters. J Biol Chem. 2011 Jan 21;286(3):2354-64.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
408.8±20.0 °C at 760 mmHg

[ Melting Point ]:
153-154ºC

[ Molecular Formula ]:
C₁₃H₁₂O₃

[ Molecular Weight ]:
216.23

[ Flash Point ]:
160.7±15.3 °C

[ Exact Mass ]:
216.078644

[ PSA ]:
46.53000

[ LogP ]:
2.65

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.625

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%