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WS 12

Names

[ CAS No. ]:
68489-09-8

[ Name ]:
WS 12

[Synonym ]:
WS 12
7-Hydroxy-DPAT hydrobromide
WS-12

Biological Activity

[Description]:

WS-12 is an agonist of TRPM8 with an EC50 of 39 nM.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel
Research Areas >> Metabolic Disease
Research Areas >> Cancer

[Target]

EC50: 39 nM (TRPM8)[1]


[References]

[1]. Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41(3):285-94.


[Related Small Molecules]

capsaicin | Capsazepine | EIPA | Diphenyleneiodonium chloride | HC-030031 | SKF-96365 | HC 067047 | AMG 9810 | GSK-1016790A | SAR7334 | PF-4840154 | RN-1734 | AMG-517 | SB-366791 | IcilinAG-3-5

Chemical & Physical Properties

[ Molecular Formula ]:
C18H27NO2

[ Molecular Weight ]:
289.41200

[ Exact Mass ]:
289.20400

[ PSA ]:
38.33000

[ LogP ]:
4.41510

[ Storage condition ]:
2-8℃

Related Compounds