Dithioerythritol

Names

[ Name ]:
Dithioerythritol

[Synonym ]:
DITHIOERYTHRITOL
DL-1,4-Dithiothreitol
DTT
MFCD00063750
1,4-Dithiothreitol
1,4-Bissulfanylbutane-2,3-diol
DL-1,4-Dimercapto-2,3-dihydroxybutane
2,3-Butanediol, 1,4-dimercapto-, (2S,3S)-
THREO-2,3-DIHYDROXY-1,4-DITHIOLBUTANE
Erythritol, 1,4-dithio-
1,4-Disulfanyl-2,3-butanediol
(2R,3S)-1,4-Disulfanylbutane-2,3-diol
Threitol, 1,4-dithio-
(R*,R*)-1,4-DIMERCAPTO-2,3-BUTANEDIOL
2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-
(2S,3S)-1,4-Disulfanyl-2,3-butanediol
Cleland's Reagent
DL-Dithiothreitol
2,3-Butanediol, 1,4-dimercapto-, (2R,3S)-rel-
(2R*,3S*)-1,4-dimercaptobutane-2,3-diol
(2S,3S)-1,4-Disulfanylbutane-2,3-diol
threo-2,3-Dihydroxy-1,4-butanedithiol
dithiothreitol
(2R*,3S*)-1,4-dimercapto-2,3-butanediol
erythro-1,4,-Dimercapto-2,3-butanediol
EINECS 229-998-8
Sputolysin
threo-1,4-Dimercapto-2,3-butanediol
(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
1,4-Disulfanylbutane-2,3-diol
2,3-Butanediol, 1,4-dimercapto-
DTE
(2R,3S)-1,4-Disulfanyl-2,3-butanediol
(±)-1,4-Dimercapto-2,3-butanediol
erythro-1,4-Dimercapto-2,3-butanediol

Biological Activity

[Description]:

DTE (Dithioerythritol) is a sulfur containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; is an epimer of dithiothreitol(DTT).

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[References]

[1]. Dithioerythritol, From Wikipedia

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
364.5±42.0 °C at 760 mmHg

[ Melting Point ]:
82-86ºC

[ Molecular Formula ]:
C₄H₁₀O₂S₂

[ Molecular Weight ]:
154.251

[ Flash Point ]:
174.2±27.9 °C

[ Exact Mass ]:
154.012222

[ PSA ]:
118.06000

[ LogP ]:
0.07

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.579

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 10 mg/mL, clear, colorless | Soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KF2410000

CHEMICAL NAME :: Erythritol, 1,4-dithio-

CAS REGISTRY NUMBER :: 6892-68-8

BEILSTEIN REFERENCE NO. :: 1719756

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H10-O2-S2

MOLECULAR WEIGHT :: 154.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 309 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: HEREAY Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 1947- Volume(issue)/page/year: 91,105,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4164 No. of Facilities: 315 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 8177 (estimated) No. of Female Employees: 5997 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
UN 3335

[ WGK Germany ]:
3

[ RTECS ]:
KF2410000

[ HS Code ]:
29309070

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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