Peonidin-3-O-glucoside chloride

Names

[ Name ]:
Peonidin-3-O-glucoside chloride

[Synonym ]:
peonidin-3-glucoside
3-(Glucosyloxy)-4',5,7-trihydroxy-3'-methoxyflavylium chloride
kuromanin chloride
Peonidin monoglucoside
Peonidin 3-O-glucoside chloride
Peonidin 3-monoglucoside
UNII-3419IIT8I0

Biological Activity

[Description]:

Peonidin 3-O-glucoside chloride, an anthocyanin, act as an insulin secretagogue. Peonidin 3-O-glucoside chloride can increase glucose uptake in HepG2 cells. Peonidin 3-O-glucoside chloride has the potential for type-2 diabetes comorbidities research[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor

[References]

[1]. Diego A Luna-Vital, et al. Anthocyanins from purple corn activate free fatty acid-receptor 1 and glucokinase enhancing in vitro insulin secretion and hepatic glucose uptake. PLoS One. 2018 Jul 11;13(7):e0200449.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃ClO₁₁

[ Molecular Weight ]:
498.86

[ Exact Mass ]:
498.09300

[ PSA ]:
182.44000

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Articles

Black rice (Oryza sativa L. indica) pigmented fraction suppresses both reactive oxygen species and nitric oxide in chemical and biological model systems.

J. Agric. Food Chem. 51(18) , 5271-7, (2003)

Anthocyanins, present in fruits and vegetables as natural colorants, have been well characterized to possess bioactive properties. Anthocyanin components extracted from black rice (Oryza sativa L. ind...

Antioxidant capacities and phenolics levels of French wines from different varieties and vintages.

J. Agric. Food Chem. 49(7) , 3341-8, (2001)

Phenolics from grapes and wines can play a role against oxidation and development of atherosclerosis. Levels of phenolics, major catechins [(+)-catechin, (-)-epicatechin, procyanidin dimers B1, B2, B3...

Peonidin 3-glucoside inhibits lung cancer metastasis by downregulation of proteinases activities and MAPK pathway.

Nutr. Cancer 62(4) , 505-16, (2010)

Anthocyanins, present in various vegetables and fruits as a nature colorant, have broad activities including anticarcinogenesis and antimutagenesis, which are generally attributed to their antioxidant...