Morantel citrate salt

Names

[ Name ]:
Morantel citrate salt

[Synonym ]:
MFCD00079447
MORANTEL CITRATE
UNII-VC8Z4SS5QX
Morantel citrate salt
EINECS 274-028-9

Biological Activity

[Description]:

Morantel citrate is a veterinary anthelmintic agent that inhibits parasitic infections in cattle, sheep and goats. Morantel citrate paralyzes the nervous system of the parasite, helping the animal expel the dead parasite from the body[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Coles GC, et al. Activity of morantel citrate against strains of benzimidazole-resistant nematodes of sheep in the United Kingdom. Vet Rec. 1993 Aug 14;133(7):156-7.

Chemical & Physical Properties

[ Boiling Point ]:
552.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₄N₂O₇S

[ Molecular Weight ]:
413.466

[ Exact Mass ]:
413.138794

[ PSA ]:
175.97000

[ LogP ]:
0.92870

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Morantel allosterically enhances channel gating of neuronal nicotinic acetylcholine alpha 3 beta 2 receptors.

Mol. Pharmacol. 74 , 466-475, (2008)

We studied allosteric potentiation of rat alpha3beta2 neuronal nicotinic acetylcholine receptors (nAChRs) by the anthelmintic compound morantel. Macroscopic currents evoked by acetylcholine (ACh) from...

Bioscience Horizons. Functional analysis of nematode nicotinic receptors James Nicholas Sleigh

Bioscience Horizons 3 , 29-39, (2010)