Z-LYS-SBZL HCL

Names

[ Name ]:
Z-LYS-SBZL HCL

[Synonym ]:
Hexanethioic acid,6-amino-2-(((phenylmethoxy)carbonyl)amino)-,S-(phenylmethyl) ester,monohydrochloride,(S)
N-|A-Cbz-L-lysine thiobenzyl ester hydrochloride
Z-L-Lys-SBzl hydrochloride
S-benzyl (2S)-6-amino-2-(phenylmethoxycarbonylamino)hexanethioate hydrochloride

Biological Activity

[Description]:

Z-LYS-SBZL (monohydrochloride) is a lysine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
566.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₇ClN₂O₃S

[ Molecular Weight ]:
422.96900

[ Flash Point ]:
296.3ºC

[ Exact Mass ]:
422.14300

[ PSA ]:
106.72000

[ LogP ]:
5.76360

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.

Biochim. Biophys. Acta 1477 , 307-323, (2000)

Natural killer (NK) and cytotoxic T-lymphocytes (CTLs) kill cells within an organism to defend it against viral infections and the growth of tumors. One mechanism of killing involves exocytosis of lym...

2-chloroadenosine stimulates granule exocytosis from mouse natural killer cells: evidence for signal transduction through a novel extracellular receptor.

Exp. Cell Res. 233 , 187-197, (1997)

The effect of 2-chloroadenosine (2CA), an adenosine receptor agonist, on the activation status of mouse natural killer (NK) cells was determined. Splenic lymphocytes incubated with 2CA exocytosed an N...

Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse.

PLoS Biol. 9 , e1001151, (2011)

Accumulation of filamentous actin (F-actin) at the immunological synapse (IS) is a prerequisite for the cytotoxic function of natural killer (NK) cells. Subsequent to reorganization of the actin netwo...