Ternidazole hydrochloride

Names

[ Name ]:
Ternidazole hydrochloride

[Synonym ]:
1H-Imidazole-1-propanol, 2-methyl-5-nitro-, hydrochloride (1:1)
3-(2-Methyl-5-nitro-1H-imidazol-1-yl)propan-1-ol hydrochloride (1:1)
EINECS 274-285-7
2-Methyl-5-nitro-1H-imidazole-1-propanol monohydrochloride
1H-Imidazole-1-propanol,2-methyl-5-nitro-,monohydrochloride
3-(2-Methyl-5-nitro-1H-imidazol-1-yl)-1-propanol hydrochloride (1:1)
Imidazole-1-propanol,2-methyl-5-nitro-,hydrochloride
Ternidazole hydrochloride

Biological Activity

[Description]:

Ternidazole hydrochloride is a hydroxymetabolite of nitroimidazole, has antiprotozoic properties[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Nathalie Mahé, et al. Solid-state studies of the triclinic (Z' = 2) antiprotozoal drug ternidazole. J Pharm Sci. 2011 Jun;100(6):2258-66.

[2]. Kamila Mitrowska, et al. Development and validation of a liquid chromatography with tandem mass spectrometry method for the determination of nitroimidazole residues in beeswax. J Sep Sci

Chemical & Physical Properties

[ Boiling Point ]:
419.9ºC at 760 mmHg

[ Molecular Formula ]:
C₇H₁₂ClN₃O₃

[ Molecular Weight ]:
221.641

[ Flash Point ]:
207.8ºC

[ Exact Mass ]:
221.056717

[ PSA ]:
83.87000

[ LogP ]:
1.80730

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI8270000

CHEMICAL NAME :: Imidazole-1-propanol, 2-methyl-5-nitro-, hydrochloride

CAS REGISTRY NUMBER :: 70028-95-4

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H11-N3-O3.Cl-H

MOLECULAR WEIGHT :: 221.67

WISWESSER LINE NOTATION :: T5N CNJ A3Q B1 ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Klebsiella pneumoniae

DOSE/DURATION :: 50 umol/L/20H

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 66,207,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport