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3'-Deoxy-5-methyluridine

Names

[ CAS No. ]:
7084-29-9

[ Name ]:
3'-Deoxy-5-methyluridine

[Synonym ]:
3'-Deoxy-5-methyluridine
5-methyl-3'-deoxy-uridine
3'-deoxythymidine
Uridine, 3'-deoxy-5-methyl-

Biological Activity

[Description]:

3’-Deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
530.01 °C(Predicted)

[ Melting Point ]:
226.62 °C

[ Molecular Formula ]:
C10H14N2O5

[ Molecular Weight ]:
242.23

[ Exact Mass ]:
242.090271

[ PSA ]:
104.55000

[ LogP ]:
-1.16

[ Index of Refraction ]:
1.584

Related Compounds