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D-Mannose-13C-1

Names

[ CAS No. ]:
70849-16-0

[ Name ]:
D-Mannose-13C-1

[Synonym ]:
C2-13C-D-glucose
2-(13)C-D-glucose
D-<1-13C>threose
<1-13C>-D-mannose
[2-13C]glucose
<1-13C>-D-threose
D-[1-13C]mannose
D-[2-13C]glucose

Biological Activity

[Description]:

D-Mannose-13C-1 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Genovese C, et al. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections. J Chemother. 2018 Apr;30(2):107-114.

Chemical & Physical Properties

[ Melting Point ]:
133ºC(lit.)

[ Molecular Formula ]:
C6H12O6

[ Molecular Weight ]:
181.14900

[ Exact Mass ]:
181.06700

[ PSA ]:
110.38000

Synthetic Route

Precursor & DownStream


Related Compounds