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12(S)-HPETE

Names

[ CAS No. ]:
71774-10-2

[ Name ]:
12(S)-HPETE

[Synonym ]:
(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
5,8,10,14-Eicosatetraenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z)-
12(S)-HPETE

Biological Activity

[Description]:

12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Nishiyama M, et al. Endothelium is required for 12-hydroperoxyeicosatetraenoic acid-induced vasoconstriction. Eur J Pharmacol. 1998 Jan 2;341(1):57-63.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
518.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O4

[ Molecular Weight ]:
336.47

[ Flash Point ]:
175.6±23.6 °C

[ Exact Mass ]:
336.230072

[ PSA ]:
66.76000

[ LogP ]:
6.26

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.513

Related Compounds