4-nitroso-7-oxa-4-azabicyclo[4.1.0]heptane

Names

[ CAS No. ]:
71785-87-0

[ Name ]:
4-nitroso-7-oxa-4-azabicyclo[4.1.0]heptane

[Synonym ]:
3,4-epoxy-1-nitroso-piperidine
N-Nitroso-3,4-epoxypiperidine
7-Oxa-3-azabicyclo(4.1.0)heptane,3-nitroso
3-Nitroso-7-oxa-3-azabicyclo(4.1.0)heptane
N-Nitroso-3,4-epoxypiperidin

Chemical & Physical Properties

[ Density]:
1.7g/cm3

[ Boiling Point ]:
274.1ºC at 760 mmHg

[ Molecular Formula ]:
C5H8N2O2

[ Molecular Weight ]:
128.12900

[ Flash Point ]:
119.6ºC

[ Exact Mass ]:
128.05900

[ PSA ]:
45.20000

[ LogP ]:
0.07880

[ Index of Refraction ]:
1.723

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RN6804000
CHEMICAL NAME :
7-Oxa-3-azabicyclo(4.1.0)heptane, 3-nitroso-
CAS REGISTRY NUMBER :
71785-87-0
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H8-N2-O2
MOLECULAR WEIGHT :
128.15
WISWESSER LINE NOTATION :
T36 BO ENTJ ENO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg/30W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - angiosarcoma

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,13,1984

Synthetic Route

Precursor & DownStream


Related Compounds