(Diacetyl)-α-MSH trifluoroacetate salt

Names

[ CAS No. ]:
71952-90-4

[ Name ]:
(Diacetyl)-α-MSH trifluoroacetate salt

[Synonym ]:
N,O-Diacetylseryltyrosylserylmethionyl-α-glutamylhistidylphenylalanylarginyltryptophylglycyllysylprolylvalinamide
Valinamide, N,O-diacetylseryltyrosylserylmethionyl-α-glutamylhistidylphenylalanylarginyltryptophylglycyllysylprolyl-

Biological Activity

[Description]:

(Diacetyl)-α-MSH is a peptide compound, which introduces an oxalyl (Diacetyl) group into the α-MSH molecule, which can increase the biological activity of the polypeptide[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. R J Arends, et al. alpha-MSH acetylation in the pituitary gland of the sea bream (Sparus aurata L.) in response to different backgrounds, confinement and air exposure. J Endocrinol. 2000 Aug;166(2):427-35.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₇₉H₁₁₁N₂₁O₂₀S

[ Molecular Weight ]:
1706.92

[ Exact Mass ]:
1705.803467

[ PSA ]:
674.35000

[ LogP ]:
-0.61

[ Index of Refraction ]:
1.674

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

A role for di-acetyl alpha-melanocyte-stimulating hormone in the control of cortisol release in the teleost Oreochromis mossambicus.

J. Endocrinol. 135(2) , 285-92, (1992)

In stressed tilapia, Oreochromis mossambicus, total alpha-melanocyte-stimulating hormone (alpha-MSH) levels and di-acetyl alpha-MSH/mono-acetyl alpha-MSH (di:mono) ratios are elevated. We therefore in...

Bromocriptine-induced changes in the biochemistry, physiology, and histology of the intermediate lobe of the rat pituitary gland.

Endocrinology 114(5) , 1871-84, (1984)

Treatment of rats with 2-Br-alpha-ergocryptine (bromocriptine; CB 154) elicits biochemical, physiological, and histological changes in the intermediate lobe (IL) of the rat pituitary gland, suggesting...

alpha-Melanocyte-stimulating hormone-like peptides in the intermediate lobe of the rat pituitary gland: characterization of content and release in vitro.

Endocrinology 112(2) , 435-41, (1983)

Reverse phase high performance liquid chromatography (HPLC) followed by RIA of the chromatographic fractions was used to separate and quantify, respectively, the alpha MSH-like peptides stored in the ...