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1-[2-(2,4-Dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H-imidazole

Names

[ CAS No. ]:
72479-26-6

[ Name ]:
1-[2-(2,4-Dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H-imidazole

[Synonym ]:
Fenticonazole [INN:BAN]
Rec 15-1476
FENTICONAZOLE
Fenticonazolum [INN-Latin]
Fenticonazol [INN-Spanish]
1-[2-(2,4-dichloro-phenyl)-2-(4-phenylsulfanyl-benzyloxy)-ethyl]-1H-imidazole
Fenticonazolum
1H-Imidazole,1-(2-(2,4-dichlorophenyl)-2-((4-(phenylthio)phenyl)methoxy)ethyl)
MFCD00865611
Fenticonazol
1-[2-(2,4-Dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H-imidazole

Biological Activity

[Description]:

Fenticonazole is an imidazole derivative with antibacterial and antifungal activity. Fenticonazole has the potential for the research of mixed vaginitis[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Tumietto F, et al. Looking for appropriateness in the cure of mixed vaginitis: the role of fenticonazole as an empiric treatment. Future Microbiol. 2019;14:1349-1355.

[2]. Veronese M, et al. Fenticonazole, a new imidazole derivative with antibacterial and antifungal activity. In vitro study. Arzneimittelforschung. 1981;31(12):2133-2137.

Chemical & Physical Properties

[ Density]:
1.26 g/cm3

[ Boiling Point ]:
637.2ºC at 760 mmHg

[ Molecular Formula ]:
C24H20Cl2N2OS

[ Molecular Weight ]:
455.39900

[ Flash Point ]:
339.2ºC

[ Exact Mass ]:
454.06700

[ PSA ]:
52.35000

[ LogP ]:
7.29920

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds