(r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine
Names
[ CAS No. ]:
72748-99-3
[ Name ]:
(r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine
[Synonym ]:
(2R)-2-(Methoxymethyl)-1-pyrrolidinamine
(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine
MFCD00010622
(2R)-2-(Methoxymethyl)pyrrolidin-1-amine
1-Pyrrolidinamine, 2-(methoxymethyl)-, (2R)-
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
183.7±13.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H14N2O
[ Molecular Weight ]:
130.188
[ Flash Point ]:
64.9±19.8 °C
[ Exact Mass ]:
130.110611
[ PSA ]:
38.49000
[ LogP ]:
-1.25
[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.470
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Nat. Rev. Drug Discov. 13(12) , 889-903, (2014)
The clinical successes of proteasome inhibitors for the treatment of cancer have highlighted the therapeutic potential of targeting this protein degradation system. However, proteasome inhibitors prev...
Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.Am. J. Physiol. Regul. Integr. Comp. Physiol. 310 , R355-65, (2016)
Amylin enhances arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei leptin signaling and synergistically reduces food intake and body weight in selectively bred diet-induced obese (DIO) rats. Sin...