AMPA/kainate antagonist-3

Names

[ Name ]:
AMPA/kainate antagonist-3

[Synonym ]:
(R)-5-(4-AMINO-3-METHYL-PHENYL)-8-METHYL-7-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-8,9-DIHYDRO-7H-1,3-DIOXOLO[4,5-H][2,3]-BENZODIAZEPINE

Biological Activity

[Description]:

BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. Wang C, et al. Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci. 2014;5(2):138-147.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₁N₅O₂S

[ Molecular Weight ]:
407.14

AMPA/kainate antagonist-3

Names

Biological Activity

Chemical & Physical Properties

Related Compounds