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Albanin A

Names

[ CAS No. ]:
73343-42-7

[ Name ]:
Albanin A

[Synonym ]:
2-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(3-methyl-but-2-enyl)-1-benzopyran-4-one
Albanin A

Biological Activity

[Description]:

Albanin A, a flavonoid, suppresses glutamate release by decreasing Ca2+/calmodulin/adenylate Cyclase 1 (AC1) activation in synaptosomes and exerts neuroprotective effect in vivo. Albanin A has anti-inflflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[References]

[1]. Yi Chang, et al. Albanin A, Derived from the Root Bark of Morus alba L., Depresses Glutamate Release in the Rat Cerebrocortical Nerve Terminals via Ca2+/Calmodulin/Adenylate Cyclase 1 Suppression. J Med Food. 2021 Mar;24(3):209-217.  

Chemical & Physical Properties

[ Density]:
1.408g/cm3

[ Boiling Point ]:
621.7ºC at 760 mmHg

[ Molecular Formula ]:
C20H18O6

[ Molecular Weight ]:
354.35300

[ Flash Point ]:
225.4ºC

[ Exact Mass ]:
354.11000

[ PSA ]:
111.13000

[ LogP ]:
3.79110

[ Index of Refraction ]:
1.678

Related Compounds